DHA Brain Support Information

NutraCups® DHA Brain Support

NutraCups® DHA Brain Support is a hot-chocolate flavored health drink, which provides health-conscious people with a unique combination of bioactive ingredients for brain and cognition support*. Our DHA Brain Support cups contain docosahexaenoic acid (DHA), superfood cocoa flavanols and a combination of vitamin C and E.

LIPOSOMA proudly announces our newest product range, called NutraCups®. LIPOSOMA’s NutraCups® DHA Brain Support with hot-chocolate taste is a functional food, owing to the uniquely combined health effects of its ingredients DHA, cocoa flavanols, and vitamin C and E. For LIPOSOMA’s NutraCups, we carefully mix and secure the finest ingredients in airtight cup cartridges to be consumed as a hot beverage after warm water extraction, using standard coffee cup extraction machines. Our technology is the first to provide a solution to combine pure, natural and delicate bioactives that are otherwise incompatible, unstable or difficult for the body to absorb. Finally, the way NutraCups® are processed and packed allows our products to remain free of preservatives.

DHA Brain Support health benefits

LIPOSOMA’s hot-chocolate flavored NutraCups® DHA Brain Support is a functional food, owing its health benefit for brain and cognitive functioning to the uniquely combined effects of its bioactive ingredients. DHA contributes to normal brain performance [1], while vitamin C supports the functioning of the nervous system [2, 3]. The nervous system and the brain have high oxygen demands, and the antioxidants vitamin C and E in this drink can contribute to scavenging free radicals in these structures [4]. Oxidative stress can play a role in cognitive problems that may arise during ageing, such as problems with memory, reasoning and problem solving [4]. The cocoa flavanols in this NutraCup are suggested to help maintain normal mental health**, as they might increase blood flow and vascular health in the brain and sensory systems, and stimulate the production of neuroprotective and neuromodulatory proteins [5].

Why in NutraCups®?

LIPOSOMA has invented a new technology enabling liposomal encapsulation of its most delicate active ingredients: NutraCups®. NutraCups are cartridges that are designed for warm water extraction using common espresso machines present in many households. The NutraCup technology allows for combining hydrophobic cocoa polyphenols, DHA, and vitamin E with hydrophilic vitamin C together in one product; ingredients which would otherwise be incompatible [6]. Moreover, liposomal encapsulation helps to increase absorption of the ingredients in this NutraCup, which shows to be beneficial for the bioavailability of cocoa flavanols in this product [7], while lecithin increases uptake of DHA [8]. Finally, the way the bioactives are encapsulated in our NutraCups® BrainSupport allows for sustained release, which reportedly results in better efficacy [7, 9, 10]. The liposomal beverage that is produced allows for the encapsulation, enhanced delivery and improved performance of many ingredients, but in particular those health ingredients that require higher daily doses.

*DHA contributes to normal brain functioning. Vitamin C contributes to maintaining normal psychological function and function of the nervous system.
**This claim is currently on hold for revision by EFSA and not yet approved.

Sources

1. Yurko-Mauro, K., Alexander, D. D., & Van Elswyk, M. E. (2015). Docosahexaenoic acid and adult memory: a systematic review and meta-analysis. PloS one, 10(3), e0120391.

2. May, J. M. (2012). Vitamin C transport and its role in the central nervous system. Water Soluble Vitamins, 85-103.

3. Travica, N., Ried, K., Sali, A., Scholey, A., Hudson, I., & Pipingas, A. (2017). Vitamin C status and cognitive function: a systematic review. Nutrients, 9(9), 960.

4. Tardy, A. L., Pouteau, E., Marquez, D., Yilmaz, C., & Scholey, A. (2020). Vitamins and minerals for energy, fatigue and cognition: A narrative review of the biochemical and clinical evidence. Nutrients, 12(1), 228.

5. Sokolov, A. N., Pavlova, M. A., Klosterhalfen, S., & Enck, P. (2013). Chocolate and the brain: neurobiological impact of cocoa flavanols on cognition and behavior. Neuroscience & Biobehavioral Reviews, 37(10), 2445-2453.

6. Bruch, G. E., Fernandes, L. F., Bassi, B. L., Alves, M. T. R., Pereira, I. O., Frézard, F., & Massensini, A. R. (2019). Liposomes for drug delivery in stroke. Brain research bulletin, 152, 246-256.

7. Mignet, N., Seguin, J., & Chabot, G. G. (2013). Bioavailability of polyphenol liposomes: a challenge ahead. Pharmaceutics, 5(3), 457-471.

8. van Wijk, N., Balvers, M., Cansev, M., Maher, T. J., Sijben, J. W., & Broersen, L. M. (2016). Dietary crude lecithin increases systemic availability of dietary docosahexaenoic acid with combined intake in rats. Lipids, 51(7), 833-846.

9. Ghosh, S., Ghosh, S., & Sil, P. C. (2019). Role of nanostructures in improvising oral medicine. Toxicology reports, 6, 358-368.

10. Fricker, G., Kromp, T., Wendel, A., Blume, A., Zirkel, J., Rebmann, H., Setzer, C., Quinkert R., Martin, F., Muller-Goymann, C. (2010). Phospholipids and lipid-based formulations in oral drug delivery. Pharmaceutical Research 27(8), 1469-1486.

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